| Specific Allele Myo5ad-15R | |
| ORNL Allele Name | Myo5ad-15DTD or Myo5a^d-15DTD |
| Belongs to Generic Allele group | Myo5ad-pl (dilute; prenatally lethal) |
| Locus Name | Myo5a= d (myosin Va = dilute) |
| Alternate Allele name | Myo5ad-15R, d15DTD, dAj1 |
| Mutation Type | Presumed Small Inversion |
| Chromosome | 9 |
| Standard Map Locations | 9/42.0 and 9/42.0 |
| Breakpoint Locations | Myo5a?; l9Rl1? |
| Molecular/physical characteristics | Does not delete probes p0.3 or p94.1. |
| Origin | ORNL, induced |
| Mutagen | X-ray |
| Fractions | 2 x 500 cGy (24-hr interval) |
| Dose Rate | ~ 90 cGy/min |
| Male Parent (Mutagenized) | (101/Rl x C3H/Rl)F1 |
| Female Parent | multiple-recessive tester (T-stock) |
| Germ-Cell Type Exposed | stem-cell spermatogonia |
| Origin Remarks | Same sire as Myo5ad-19DTD. |
Oak Ridge Publications regarding Myo5ad-15DTD |
|
| Russell, L. B., Mutation Res. 11:107-123, 1971. | |
| Kingsley, D. M., et al., EMBO J. 9: 395-399, 1990. | |
| Rinchik, E. M., et al., Genetics 112:321-342, 1986. | |
| ORNL Stock Name Formal Name |
15DTD STOCK Myo5ad-15R +/Myo5ad Bmp5se or STOCK Myo5ad-15R +/ + Bmp5se |
| ORNL Availability | Frozen Embryos, Frozen Sperm, Frozen Tissues |
| ORNL Strain Type | Non-Inbred |
| Genotype | Phenotypes involving Myo5ad-15DTD | ||
|---|---|---|---|
| Code | Code Definition | Additional Comments | |
| Myo5ad-15DTD/+ | 0 | Appears wild-type | |
| Myo5ad-15DTD/Myo5ad-15DTD | 18A | Prenatal lethality | |
| Myo5ad-15DTD/Myo5ad | 1A | Hair pigment reduced or altered all over | Pigmentation like Myo5ad/Myo5ad. |
| Myo5ad-15DTD hemizygous | 18A | Prenatal lethality | |
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