Specific Allele Myo5ad-22R
ORNL Allele NameMyo5ad-19DTD or Myo5a^d-19DTD
Belongs to Generic Allele group Myo5ad-pl (dilute; prenatally lethal)
Locus Name Myo5a= d  (myosin Va = dilute)
     Alternate Allele name Myo5ad-22R,  d19DTD
Mutation Type Presumed Small Inversion
     Chromosome 9  
     Standard Map Location 9/42.0
     Breakpoint Locations Myo5a?; l9Rl1?
Origin ORNL, induced
     Mutagen X-ray
     Fractions 2 x 500 cGy (24-hr interval)
     Dose Rate ~ 90 cGy/min
     Male Parent (Mutagenized) (101/Rl x C3H/Rl)F1
     Female Parent multiple-recessive tester (T-stock)
     Germ-Cell Type Exposed stem-cell spermatogonia
     Origin Remarks Same sire as Myo5ad-15DTD. Until specifically tested, assume same rearrangement.
Oak Ridge Publications regarding Myo5ad-19DTD
Russell, L. B., Mutation Res. 11:107-123, 1971.
Rinchik, E. M., et al., Genetics 112:321-342, 1986.
ORNL Stock Name
     Formal Name
19DTD
STOCK Myo5ad-22R +/Myo5ad Bmp5se or STOCK Myo5ad-22R +/ + Bmp5se
     ORNL Availability Frozen Embryos,
Frozen Sperm,
Frozen Ovaries,
Frozen Tissues
     ORNL Strain Type Non-Inbred


Genotype Phenotypes involving Myo5ad-19DTD
Code Code Definition Additional Comments
Myo5ad-19DTD/+ 0 Appears wild-type  
Myo5ad-19DTD/Myo5ad-19DTD 18A Prenatal lethality  
Myo5ad-19DTD/Myo5ad 1A Hair pigment reduced or altered all over Pigmentation like Myo5ad/Myo5ad.
Myo5ad-19DTD hemizygous 18A Prenatal lethality  


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