| Specific Allele Myo5ad-26R | |
| ORNL Allele Name | Myo5ad-19Zb or Myo5a^d-19Zb |
| Belongs to Generic Allele group | Myo5ad-pl (dilute; prenatally lethal) |
| Locus Name | Myo5a= d (myosin Va = dilute) |
| Alternate Allele name | Myo5ad-26R, d19Zb, dAc2 |
| Mutation Type | Multi-Locus Deletion |
| Chromosome | 9 |
| Molecular/physical characteristics | Deletes probes p94.1 and pl.3. |
| Nearest Non-deleted Sites | l9Rl2) --- deletion --- (l9Rl4 |
| Farthest Deleted Sites | (l9Rl7 - l9Rl8) |
| Origin | ORNL, induced |
| Mutagen | X-ray |
| Fractions | 1 x 400 cGy |
| Dose Rate | ~ 90 cGy/min |
| Male Parent | multiple-recessive tester (T-stock) |
| Female Parent (Mutagenized) | (101/Rl x C3H/Rl)F1 |
| Germ-Cell Type Exposed | maturing oocytes |
Oak Ridge Publications regarding Myo5ad-19Zb |
|
| Russell, L. B., Mutation Res. 11:107-123, 1971. | |
| Kingsley, D. M., et al., EMBO J. 9: 395-399, 1990. | |
| Rinchik, E. M., et al., Genetics 112:321-342, 1986. | |
| ORNL Stock Name Formal Name |
19Zb STOCK Myo5ad-26R +/Myo5ad Bmp5se or STOCK Myo5ad-26R +/ + Bmp5se |
| ORNL Availability | Frozen Embryos, Frozen Sperm, Frozen Tissues |
| ORNL Strain Type | Non-Inbred |
| Genotype | Phenotypes involving Myo5ad-19Zb | ||
|---|---|---|---|
| Code | Code Definition | Additional Comments | |
| Myo5ad-19Zb/+ | 0 | Appears wild-type | |
| Myo5ad-19Zb/Myo5ad-19Zb | 18A | Prenatal lethality | |
| Myo5ad-19Zb/Myo5ad | 1A | Hair pigment reduced or altered all over | Pigmentation like Myo5ad/Myo5ad. |
| Myo5ad-19Zb hemizygous | 18A | Prenatal lethality | |
Generic Alleles at Myo5a
Specific Myo5ad-pl Alleles