Specific Allele Myo5a^d-1CHLg

Specific Allele Myo5a^d-28R
ORNL Allele Name	Myo5a^d-1CHLg or Myo5a^d-1CHLg
Belongs to Generic Allele group	Myo5a^d-pl (dilute; prenatally lethal)
Locus Name	Myo5a= d (myosin Va = dilute)
Alternate Allele name	Myo5a^d-28R, d^1CHLg, d^OR-37Q
Mutation Type	Multi-Locus Deletion
Chromosome	9
Nearest Non-deleted Sites	Rab27a) --- deletion --- (Bmp5
Farthest Deleted Sites	(l9Rl2 - p0.3)
Origin	ORNL, induced
Mutagen	chlorambucil
Fractions	1 x 10 mg/kg
Delivery	intraperitoneal injection
Male Parent (Mutagenized)	(101/Rl x C3H/Rl)F₁
Female Parent	multiple-recessive tester (T-stock)
Germ-Cell Type Exposed	early spermatid
Oak Ridge Publication	Rinchik, E. M., et al., Proc. Natl. Acad. Sci., USA, 87: 1416-1420, 1990.
ORNL Stock Name Formal Name	1CHLg STOCK Myo5a^d-28R +/Myo5a^d Bmp5^se or STOCK Myo5a^d-28R +/ + Bmp5^se
ORNL Availability	Frozen Embryos, Frozen Sperm, Frozen Tissues
ORNL Strain Type	Non-Inbred

Genotype	Phenotypes involving Myo5a^d-1CHLg
Genotype	Code	Code Definition	Additional Comments
Myo5a^d-1CHLg/+	0	Appears wild-type
Myo5a^d-1CHLg/Myo5a^d-1CHLg	18A	Prenatal lethality
Myo5a^d-1CHLg/Myo5a^d	1A	Hair pigment reduced or altered all over	Pigmentation like Myo5a^d/Myo5a^d.
Myo5a^d-1CHLg hemizygous	18A	Prenatal lethality