| Specific Allele Myo5ad-49R | |
| ORNL Allele Name | Myo5ad-2CHLe or Myo5a^d-2CHLe |
| Belongs to Generic Allele group | Myo5ad-pl (dilute; prenatally lethal) |
| Locus Name | Myo5a= d (myosin Va = dilute) |
| Alternate Allele name | Myo5ad-49R, d2CHLe, dAk, dOR-18Q |
| Mutation Type | Multi-Locus Deletion |
| Chromosome | 9 |
| Molecular/physical characteristics | Deletes probe p94.1 but not p0.3 |
| Nearest Non-deleted Sites | not tested) --- deletion --- (p0.3 |
| Farthest Deleted Sites | (Rora - Myo5a) |
| Origin | ORNL, induced |
| Mutagen | chlorambucil |
| Fractions | 1 x 10 mg/kg |
| Delivery | intraperitoneal injection |
| Male Parent (Mutagenized) | (101/Rl x C3H/Rl)F1 |
| Female Parent | multiple-recessive tester (T-stock) |
| Germ-Cell Type Exposed | spermatozoa (or late spermatids) |
| Oak Ridge Publication | Rinchik, E. M., et al., Proc. Natl. Acad. Sci., USA, 87: 1416-1420, 1990. |
| ORNL Stock Name Formal Name |
2CHLe STOCK Myo5ad-49R +/Myo5ad Bmp5se or STOCK Myo5ad-49R +/ + Bmp5se |
| ORNL Availability | Frozen Sperm, Frozen Ovaries, Frozen Tissues |
| ORNL Strain Type | Non-Inbred |
| Genotype | Phenotypes involving Myo5ad-2CHLe | ||
|---|---|---|---|
| Code | Code Definition | Additional Comments | |
| Myo5ad-2CHLe/+ | 0 | Appears wild-type | |
| Myo5ad-2CHLe/Myo5ad-2CHLe | 18A | Prenatal lethality | |
| Myo5ad-2CHLe/Myo5ad | 1A | Hair pigment reduced or altered all over | Pigmentation like Myo5ad/Myo5ad. |
| Myo5ad-2CHLe hemizygous | 18A | Prenatal lethality | |
Mutant Mouse Database Home Page
Database Search
Generic Alleles at Myo5a
Specific Myo5ad-pl Alleles