| Specific Allele Myo5ad-64R | |
| ORNL Allele Name | Myo5ad-3FrS or Myo5a^d-3FrS |
| Belongs to Generic Allele group | Myo5ad-pl (dilute; prenatally lethal) |
| Locus Name | Myo5a= d (myosin Va = dilute) |
| Alternate Allele name | Myo5ad-64R, d3FrS, dAf1 |
| Mutation Type | Multi-Locus Deletion |
| Chromosome | 9 |
| Molecular/physical characteristics | Deletes probes p94.1 and p0.3 |
| Nearest Non-deleted Sites | Rab27a) --- deletion --- (l9Rl8 |
| Farthest Deleted Sites | (l9Rl2 - p0.3) |
| Origin | ORNL, induced |
| Mutagen | gamma rays (137Cs) |
| Fractions | 1 x 600 cGy |
| Delivery | 0.001 cGy/min |
| Male Parent (Mutagenized) | (101/Rl x C3H/Rl)F1 |
| Female Parent | multiple-recessive tester (T-stock) |
| Germ-Cell Type Exposed | stem-cell spermatogonia |
Oak Ridge Publications regarding Myo5ad-3FrS |
|
| Russell, L. B., Mutation Res. 11:107-123, 1971. | |
| Kingsley, D. M., et al., EMBO J. 9: 395-399, 1990. | |
| Rinchik, E. M., et al., Genetics 112:321-342, 1986. | |
| ORNL Stock Name Formal Name |
3FrS STOCK Myo5ad-64R +/Myo5ad Bmp5se or STOCK Myo5ad-64R +/ + Bmp5se |
| ORNL Availability | Frozen Embryos, Frozen Sperm, Frozen Tissues |
| ORNL Strain Type | Non-Inbred |
| Genotype | Phenotypes involving Myo5ad-3FrS | ||
|---|---|---|---|
| Code | Code Definition | Additional Comments | |
| Myo5ad-3FrS/+ | 0 | Appears wild-type | |
| Myo5ad-3FrS/Myo5ad-3FrS | 18A | Prenatal lethality | |
| Myo5ad-3FrS/Myo5ad | 1A | Hair pigment reduced or altered all over | Pigmentation like Myo5ad/Myo5ad. |
| Myo5ad-3FrS hemizygous | 18A | Prenatal lethality | |
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