| Specific Allele Myo5ad-66R | |
| ORNL Allele Name | Myo5ad-3MLP5 or Myo5a^d-3MLP5 |
| Belongs to Generic Allele group | Myo5ad-pl (dilute; prenatally lethal) |
| Locus Name | Myo5a= d (myosin Va = dilute) |
| Alternate Allele name | Myo5ad-66R, d3MLP5, dAh, dOR-3M5 |
| Mutation Type | Multi-Locus Deletion |
| Chromosome | 9 |
| Molecular/physical characteristics | Deletes probe p0.3 |
| Nearest Non-deleted Sites | Rab27a) --- deletion --- (Bmp5 |
| Farthest Deleted Sites | (l9Rl2 - l9Rl4) |
| Origin | ORNL, induced |
| Mutagen | melphalan |
| Fractions | 5 mg/kg |
| Delivery | intraperitoneal injection |
| Male Parent (Mutagenized) | (101/Rl x C3H/Rl)F1 |
| Female Parent | multiple-recessive tester (T-stock) |
| Germ-Cell Type Exposed | stem-cell spermatogonia |
| Oak Ridge Publication | Russell, L. B., et al., Proc. Natl. Acad. Sci. , USA 89: 6182-6186, 1992. |
| ORNL Stock Name Formal Name |
3MLP5 |
| ORNL Availability | Frozen Sperm, Frozen Ovaries, Frozen Tissues |
| Genotype | Phenotypes involving Myo5ad-3MLP5 | ||
|---|---|---|---|
| Code | Code Definition | Additional Comments | |
| Myo5ad-3MLP5/+ | 0 | Appears wild-type | |
| Myo5ad-3MLP5/Myo5ad-3MLP5 | 18A | Prenatal lethality | |
| Myo5ad-3MLP5/Myo5ad | 1A | Hair pigment reduced or altered all over | Pigmentation like Myo5ad/Myo5ad. |
| Myo5ad-3MLP5 hemizygous | 18A | Prenatal lethality | |
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