Specific Allele Myo5a^d-7G

Specific Allele Myo5a^d-89R
ORNL Allele Name	Myo5a^d-7G or Myo5a^d-7G
Belongs to Generic Allele group	Myo5a^d-pl (dilute; prenatally lethal)
Locus Name	Myo5a= d (myosin Va = dilute)
Alternate Allele name	Myo5a^d-89R, d^7G, d^Aa1
Mutation Type	Multi-Locus Deletion
Chromosome	9
Molecular/physical characteristics	Does not delete probe p94.1 or p0.3
Nearest Non-deleted Sites	p94.1) --- deletion --- (p0.3
Farthest Deleted Sites	(l9Rl3 - Myo5a)
Origin	ORNL, spontaneous
Male Parent (Mutagenized)	(101/Rl x C3H/Rl)F₁
Female Parent	multiple-recessive tester (T-stock)
Origin Remarks	Primary mutant had irradiated sire, but it was part of a mutant cluster in offspring of postmeiotically irradiated germ cells and was therefore of spontaneous origin.
Oak Ridge Publications regarding Myo5a^d-7G
Russell, L. B., Mutation Res. 11:107-123, 1971.
Kingsley, D. M., et al., EMBO J. 9: 395-399, 1990.
Rinchik, E. M., et al., Genetics 112:321-342, 1986.
ORNL Stock Name Formal Name	7G STOCK Myo5a^d-89R +/Myo5a^d Bmp5^se or STOCK Myo5a^d-89R +/ + Bmp5^se
ORNL Availability	Frozen Sperm, Frozen Ovaries, Frozen Tissues
ORNL Strain Type	Non-Inbred

Genotype	Phenotypes involving Myo5a^d-7G
Genotype	Code	Code Definition	Additional Comments
Myo5a^d-7G/+	0	Appears wild-type
Myo5a^d-7G/Myo5a^d-7G	18A	Prenatal lethality
Myo5a^d-7G/Myo5a^d	1A	Hair pigment reduced or altered all over	Like Myo5a^d/Myo5a^d.
Myo5a^d-7G hemizygous	18A	Prenatal lethality